When do you check tumor markers after orchiectomy?

When should a tumor marker be tested?

You may need a tumor marker test if you are currently being treated for cancer, have finished cancer treatment, or have a high risk of getting cancer because of family history or other reasons. The type of test you get will depend on your health, health history, and symptoms you may have.

Is there a tumor marker for testicular cancer?

There are three important tumor markers for testicular cancer: Alpha-fetoprotein (AFP) Human chorionic gonadotropin (HCG) Lactate dehydrogenase (LDH)

What tumor marker is commonly elevated in males with a testicular germ cell tumor?

High levels of any one of three tumor markers, called alpha-fetoprotein (AFP), beta human chorionic gonadotropin (hCG), and lactate dehydrogenase (LDH), may indicate a germ cell tumor.

Which of the following is a tumor marker of Nonseminomatous germ cell tumors?

Serum hCG and AFP are the most important tumor markers. AFP levels are elevated in 50-70% of patients with NSGTs, and hCG levels are elevated in 40%-60%. AFP has a half-life of 5-7 days, and hCG has a half-life of 24-48 hours.

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What is a bad CA 125 level?

In the patient who is being evaluated for a pelvic mass, a CA 125 level greater than 65 is associated with malignancy in approximately 90% of cases. However, without an obvious pelvic mass, this association is much weaker.

Are tumor marker tests reliable?

Some may be done to learn more about the cancer when it is first diagnosed. However, the presence or amount of a tumor marker alone is not enough to diagnose cancer.” There has been no evidence to prove that tumor markers are 100 percent reliable for determining the presence or absence of cancer.

Does testicular cancer spread quickly?

Seminomas tend to grow and spread more slowly than nonseminomas, which are more common, accounting for roughly 60 percent of all testicular cancers. How quickly a cancer spreads will vary from patient to patient.

Is hCG a tumor marker?

Since hCG is not normally present in men or non-pregnant women, it is useful as a tumor marker. If the tumor or cancer is producing hCG, then the hCG test can be used to help detect and monitor tumor activity.

How many stages of testicular cancer are there?

The results are combined to determine the stage of cancer for each person. There are 3 stages of testicular cancer: stages I, II, and III (1, 2, and 3). The stage provides a common way of describing how advanced the cancer is so that doctors can work together to plan the best treatment.

Which is worse seminoma or nonseminoma?

Seminomas are very sensitive to radiation therapy. Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas.

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What do Tumour markers indicate?

A tumor marker is anything present in or produced by cancer cells or other cells of the body in response to cancer or certain benign (noncancerous) conditions that provides information about a cancer, such as how aggressive it is, what kind of treatment it may respond to, or whether it is responding to treatment.

What is normal AFP tumor marker?

An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).