What is the prognosis for high grade bladder cancer?
T1Hg bladder cancer progresses to muscle-invasive or metastatic disease at a rate of 30% to 50% after 5 years. As a result, some studies advocate initial cystectomy based on the perceived acceptable morbidity and a 5-year disease-specific survival rate of 80% to 90%.
Is it common for bladder cancer to come back?
Low-grade bladder cancers recur frequently, and recurrences require treatment with a procedure called transurethral resection for bladder tumor, or TURBT. Some patients experience multiple recurrences and, as a result, undergo repeated surgeries.
Are most bladder cancers High Grade?
Bladder cancer can also be described as either low grade or high grade. Low grade bladder cancer means that your cancer is less likely to grow, spread and come back after treatment.
How serious is high grade bladder cancer?
It has not grown in toward the hollow part of the bladder, and it has not spread to the thick layer of muscle or connective tissue of the bladder (Tis, N0, M0). This is always a high-grade cancer (see “Grades,” below) and is considered an aggressive disease because it can lead to muscle-invasive disease.
What is the best treatment for high grade bladder cancer?
In general, the main treatment options for bladder cancer are:
- Immunotherapy (local and systemic)
- Targeted therapy.
- Radiation therapy.
What are the chances of dying from bladder cancer?
The general 5-year survival rate for people with bladder cancer is 77%. However, survival rates depend on many factors, including the type and stage of bladder cancer that is diagnosed. The 5-year survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%.
How quickly does bladder cancer come back?
Nearly three-fourths of patients diagnosed with high-risk bladder cancer will recur, progress, or die within ten years of their diagnosis. Even though most patients do not die of bladder cancer, the vast majority endures the morbidity of recurrence and progression of their cancer.
How often does high grade bladder cancer return?
High-grade T1 cancers recur at a rate of about 45% and 17% of these will probably progress to a higher stage. Once diagnosed, the rates of survival are quite favorable for patients with NMIBC. Survival in high-grade disease ranges from about 70-85% at 10 years and a much higher rate for low-grade disease.
What are the signs that bladder cancer has returned?
During follow-up care, a doctor familiar with your medical history can give you personalized information about your risk of recurrence. Tell your doctor about any new symptoms, such as pain during urination, blood in the urine, frequent urination, an immediate need to urinate, and any other symptoms.