Question: What is renal clear cell carcinoma?

Is clear cell renal carcinoma aggressive?

These tumors are rare, accounting for only 3 to 5 percent of RCC tumors, but they can be quite aggressive and require prompt treatment.

What causes clear cell renal carcinoma?

Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.

Can clear cell renal carcinoma be cured?

RCC can often be cured if it is diagnosed and treated surgically while still confined to the kidney and the immediately surrounding tissue. The probability of a cure is commensurate with the degree or stage of tumor dissemination.

How bad is clear cell renal cell carcinoma?

Patients with clear cell renal cell carcinoma (CCRCC) tend to have a worse prognosis than patients with other histologic subtypes of RCC, with 5-year disease-specific survival rates of 50-69%, compared with 67-87% for papillary RCC and 78-87% for chRCC.

How aggressive is clear cell carcinoma?

Clear cell carcinoma comprises a rare yet an aggressive subtype, accounting for less than 5% of all uterine carcinomas.

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How serious is clear cell carcinoma?

Patients with clear cell renal cell carcinoma (CCRCC) tend to have a worse prognosis than patients with other histologic subtypes of RCC, with 5-year disease-specific survival rates of 50-69%, compared with 67-87% for papillary RCC and 78-87% for chRCC.

How fast does clear cell renal carcinoma grow?

Clear cell carcinoma (0.86 cm/year) tended to grow faster than papillary cell carcinoma (0.28 cm/year) (P = 0.066). The mean growth rate of grade 2 tumors (0.88 cm/year) was faster than that of grade 1 tumors (0.36 cm/year) (P = 0.041).

Can clear cell renal cell carcinoma spread?

Clear cell renal carcinoma is known for its propensity for metastatic spread. Common sites of metastasis are the lungs, bones, lymph nodes, liver, adrenals and brain, but all organs can be affected. Contralateral ureteral metastasis is a rare phenomenon, and only a few cases have been reported in the literature.

Is clear cell carcinoma rare?

How common is ccRCC? In adults, ccRCC is the most common type of kidney cancer, and makes up about 80% of all renal cell carcinoma cases. ccRCC is more common in adults than children.

What is the most common treatment for renal cell carcinoma?

Surgical resection remains the only known effective treatment for localized renal cell carcinoma, and it also is used for palliation in metastatic disease. Partial or radical nephrectomy may be used, depending on tumor and patient characteristics. Open, laparoscopic, or robotic surgical techniques may be used.

How long can you live with stage 4 renal cell carcinoma?

The five-year survival rate in this stage drops to 8 percent. That means that out of 100 people, 8 people diagnosed with stage 4 cancer will still be living five years after receiving their diagnosis.

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