What is the importance of melanin with regard to skin cancer?
Why is melanin important? The essential function of melanin is to protect our skin from the damaging UV rays in sunlight. UV exposure is the largest environmental factor that initiates skin cancers, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma.
What is the role of melanin in the skin?
In addition to providing pigmentation in humans and animals, melanin also plays an important biological role by providing protection against damage from the sun. Protection against UV light. Melanin helps protect the cells of the epidermis, or outer layer of the skin, from UV light.
What are the disadvantages of melanin?
A disadvantage to having more melanin is that it makes skin more “reactive.” That means almost any stimulus–a rash, scratch, pimple, or inflammation– may trigger the production of excess melanin, resulting in dark marks or patches on the skin.
How can I stop my skin from darkening?
Protect your skin and prevent unwanted tanning with proper sun protection. Always wear a hat, sun protective clothing, and sunscreen when outside. Sunscreen should be reapplied every two hours. The American Academy of Dermatology recommends using sunscreen every day to best protect your skin.
Is melanin good or bad?
Melanin is a protective pigment in skin, blocking UV radiation from damaging DNA and potentially causing skin cancer. Melanin does protect us, but this research shows it can also do us harm.
Can you live without melanin?
Melanin is a vital pigment producing compound responsible for determining the colour of skin and hair. A deficiency in melanin can lead to several disorders and diseases. For example, a complete absence of melanin causes a condition called albinism.
Melanin is produced within the skin in cells called melanocytes and it is the main determinant of the skin color of darker-skin humans. The skin color of people with light skin is determined mainly by the bluish-white connective tissue under the dermis and by the hemoglobin circulating in the veins of the dermis.
What happens when skin is exposed to UV light?
Exposure to UV rays can cause premature aging of the skin and signs of sun damage such as wrinkles, leathery skin, liver spots, actinic keratosis, and solar elastosis. UV rays can also cause eye problems.
What light Cannot cause skin cancer?
Most skin cancers are caused by exposure to ultraviolet (UV) light. When you don’t protect your skin, UV rays from sunlight or tanning beds can damage your skin’s DNA. When the DNA is altered, it can’t properly control skin cell growth, leading to cancer.
Does UV light give you cancer?
Damage from UV exposure is cumulative and increases your skin cancer risk over time. While your body can repair some of the DNA damage in skin cells, it can’t repair all of it. The unrepaired damage builds up over time and triggers mutations that cause skin cells to multiply rapidly. That can lead to malignant tumors.