What are the long term effects of cisplatin?
Cisplatin (CDDP) is a frequently employed chemotherapeutic drug both in curative and palliative settings. When cancer patients are cured due to CDDP therapy, they unfortunately often experience severe long‐term side effects including irreversible hearing loss (ototoxicity) and permanent neuronal and renal damage.
How long does it take to recover from cisplatin?
Nadir: Meaning low point, is the point in time between chemotherapy cycles in which you experience low blood counts. Nadir: 18-23 days. Recovery: 39 days.
How long does cisplatin side effects last?
Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours. Various degrees of vomiting, nausea and/or anorexia may persist for up to 1 week after treatment.
Is cisplatin a strong chemo drug?
Cisplatin is a potent chemotherapeutic drug that has shown efficacy for the treatment of many malignancies including head and neck, ovarian, sarcomas, lymphoma, and prostate cancer.
Does Chemo shorten your life?
During the 3 decades, the proportion of survivors treated with chemotherapy alone increased (from 18% in 1970-1979 to 54% in 1990-1999), and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).
Does chemo permanently damage immune system?
Now, new research suggests that the effects of chemotherapy can compromise part of the immune system for up to nine months after treatment, leaving patients vulnerable to infections – at least when it comes to early-stage breast cancer patients who’ve been treated with a certain type of chemotherapy.
How long does cisplatin chemo stay in your body?
The chemotherapy itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience. Not all patients will experience all side effects but many will experience at least a few.
Will I lose my hair with cisplatin?
v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment.
How many cycles of cisplatin can you have?
You usually have between 4 to 6 cycles of treatment taking from 3 to 6 months. You have gemcitabine as a drip into your bloodstream over 30 minutes. You have cisplatin as a drip into your bloodstream over 1 to 4 hours.
How bad is cisplatin?
Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, or weakness.
How long does it take to feel normal after chemo?
Most people say it takes 6 to 12 months after they finish chemotherapy before they truly feel like themselves again. Read the resource Managing Cognitive Changes: Information for Cancer Survivors for more information about managing chemo brain.
Is cisplatin hard on your kidneys?
In addition, cisplatin may cause renal vasoconstriction through injury on the renal vasculature, which reduces blood flow, causing ischemic damage to the kidney and affects the glomerular filtration rate. Finally, a series of adverse reactions trigger acute renal failure.