What happens to dead cells after chemo?
Researchers from Harvard Medical School, Boston, and the Institute for Systems Biology, Seattle, have discovered that the remains of tumor cells killed by chemotherapy or other cancer treatments can actually stimulate tumor growth by inducing an inflammatory reaction.
Do cancer cells undergo cellular death?
During further tumor progression, cancer cells frequently respond to their altered state by undergoing programmed cell death and remain highly dependent on certain survival signals from their environment.
Does chemo cause necrosis or apoptosis?
Chemo drugs often kill cancer cells via necrosis, resulting in release of cell debris and various immunogenic components to stimulate immune functions and inflammatory response of the patient, which in turn will elicit cancer cell specific killing.
How fast does chemo work to shrink tumors?
In general, chemotherapy can take about 3 to 6 months to complete. It may take more or less time, depending on the type of chemo and the stage of your condition. It’s also broken down into cycles, which last 2 to 6 weeks each.
How long does it take to stop chemo?
Most people say it takes 6 to 12 months after they finish chemotherapy before they truly feel like themselves again.
Does chemotherapy cause apoptosis?
The faster that cancer cells divide, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis). Chemotherapy drugs that kill cancer cells only when they are dividing are called cell-cycle specific.
Does chemotherapy trigger apoptosis?
Several reports have suggested that anticancer drugs kill susceptible cells by inducing expression of death receptor ligands, especially Fas ligand (FasL). Other reports have indicated that chemotherapeutic agents trigger apoptosis by inducing release of cytochrome c from mitochondria.